Group Sequential Design Class for Clinical Trials
Generic function that calculates the probability to declare efficacy a...
Function for calculating the probability for efficacy given known info...
Function that calculates the cumulative probabilities to declare effic...
Function that plots the efficacy and futility boundaries
Function that displays the features of the design
seqmon
Function that sets the noncentrality parameter
Function that sets the look times
Function that shows the cumulative probabilities for efficacy and futi...
Function that sets the current look number
Function that sets the date stamp of the design object
Function that calculates the lower boundaries for futility
The default beta spending function
Function for calculating the efficacy and futility boundaries
Function that calculates the upper boundaries for efficacy
The default alpha spending function
Generic function that calculates boundary crossing probabilities used ...
Class "sequential.design"
The sequential design class
Function that Sets the expression of the base alpha spending function ...
Function that sets the base alpha spending function
Function that sets the base beta spending function
Function that sets the expression of the base beta spending function a...
Function that updates the design
S4 class object for creating and managing group sequential designs. It calculates the efficacy and futility boundaries at each look. It allows modifying the design and tracking the design update history.