seqmon2.5 package

Group Sequential Design Class for Clinical Trials

curtail

Generic function that calculates the probability to declare efficacy a...

curtailDesign

Function for calculating the probability for efficacy given known info...

getProbabilities

Function that calculates the cumulative probabilities to declare effic...

plotBoundaries

Function that plots the efficacy and futility boundaries

printDesign

Function that displays the features of the design

seqmon-package

seqmon

setNoncentrality

Function that sets the noncentrality parameter

setTimes

Function that sets the look times

summaryDesign

Function that shows the cumulative probabilities for efficacy and futi...

setCurrentLook

Function that sets the current look number

setDatestamp

Function that sets the date stamp of the design object

betaspend

Function that calculates the lower boundaries for futility

betaspendf

The default beta spending function

calcBoundaries

Function for calculating the efficacy and futility boundaries

alphaspend

Function that calculates the upper boundaries for efficacy

alphaspendf

The default alpha spending function

seqmon

Generic function that calculates boundary crossing probabilities used ...

sequential.design-class

Class "sequential.design"

sequential.design

The sequential design class

setAlphaspendfString

Function that Sets the expression of the base alpha spending function ...

setBaseAlphaspendf

Function that sets the base alpha spending function

setBaseBetaspendf

Function that sets the base beta spending function

setBetaspendfString

Function that sets the expression of the base beta spending function a...

updateDesign

Function that updates the design

S4 class object for creating and managing group sequential designs. It calculates the efficacy and futility boundaries at each look. It allows modifying the design and tracking the design update history.

  • Maintainer: Hui Zheng
  • License: MIT + file LICENSE
  • Last published: 2024-05-17