Sparse Marginal Epistasis Test
Estimate Memory Requirements for SME Routine
Create an HDF5 File
Read Dataset from an HDF5 File
Simulate Quantitative Traits from PLINK Genotypes
Sparse Marginal Epistasis Test (SME)
Write Data to an HDF5 Dataset
The Sparse Marginal Epistasis Test is a computationally efficient genetics method which detects statistical epistasis in complex traits; see Stamp et al. (2025, <doi:10.1101/2025.01.11.632557>) for details.
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