tmod0.50.13 package

Feature Set Enrichment Analysis for Metabolomics and Transcriptomics

check_tmod_gs

Check an object of class tmodGS

eigengene

Calculate the eigengene of a module from a data set

evidencePlot

Create an evidence plot for a module

filterGS

Filter by genes belonging to a gene set from a data frame

getGenes

Get genes belonging to a gene set

getModuleMembers

Return the contents of a gene set

ggEvidencePlot

Create an evidence plot for a module (ggplot2 version)

ggPanelplot

Create a tmod panel plot using ggplot

hgEnrichmentPlot

Create a visualisation of enrichment

makeTmodFromDataFrame

Convert a data frame to a tmod object

modCorPlot

Plot a correlation heatmap for modules

modcors

Module correlation

modGroups

Find group of modules

modjaccard

Jaccard index for modules

modOverlaps

Calculate overlaps of the modules

pcaplot

Plot a PCA object returned by prcomp

pvalEffectPlot

Create an effect size / p-value plot

showGene

A combined beeswarm / boxplot

simplePie

Simple Pie Chart

tmod-data

Default gene expression module data

tmod-package

Transcriptional Module Analysis

tmod_ids

Query and set IDs of gene sets in a tmodGS object

tmod2DataFrame

Convert a tmod module set into a data frame

tmod2tmodGS

Convert the old tmod objects to the tmodGS objects

tmodAUC

Calculate AUC

tmodDecideTests

Count the Up- or Down-regulated genes per module

tmodGS-class

S3 class for tmod gene set collections

tmodImportMSigDB

Import data from MSigDB

tmodLEA

Leading Edge Analysis

tmodLEASummary

Summary stats of a leading edge analysis

tmodLimmaDecideTests

Up- and down-regulated genes in modules based on limma object

tmodLimmaTest

Run tmod enrichment tests directly on a limma object

tmodLimmaTopTable

tmod's replacement for the limma topTable function

tmodPal

A selection of color palettes

tmodPanelPlot

Plot a summary of multiple tmod analyses

tmodPCA

PCA plot annotated with tmod

tmodSummary

Create a summary of multiple tmod analyses

tmodTagcloud

Tag cloud based on tmod results

tmodUtest

Perform a statistical test of module expression

upset

Upset plot

Methods and feature set definitions for feature or gene set enrichment analysis in transcriptional and metabolic profiling data. Package includes tests for enrichment based on ranked lists of features, functions for visualisation and multivariate functional analysis. See Zyla et al (2019) <doi:10.1093/bioinformatics/btz447>.

  • Maintainer: January Weiner
  • License: GPL (>= 2.0)
  • Last published: 2023-03-31