Two-/Three-Stage Designs for Phase 1&2 Clinical Trials
Zhong's 2-/3- stage Phase II design
run dose-finding simulations
generate three-stage dose-finding decision table
Zhong's 2-/3- stage Phase II design
plot simulation results from a dec.sim object
plot decision table from a "dec.table" object.
print decision table from a "dec.table" object.
print Zhong's design from a "opt.design" object.
Dose-finding simulations for a list of scenarios
Summarizing simulation results from a dec.sim object
Calculate optimal Zhong's two-/three-stage Phase II designs (see Zhong (2012) <doi:10.1016/j.cct.2012.07.006>). Generate Target Toxicity decision table for Phase I dose-finding (two-/three-stage). This package also allows users to run dose-finding simulations based on customized decision table.