'VigiBase' Pharmacovigilance Database Toolbox
Add adverse drug reaction column(s) to a dataset
Add drug dose column(s) to a dataset, in milligram per day
Add drug column(s) to a dataset
Add indication column(s) to a dataset
Fast formatting of numbers
Check binary variables
Compute disproportionality
Compute interaction disproportionality
Compute (r)OR from a model summary
Example source tables for VigiBase and MedDRA
Summarise continuous variables
Dechallenge descriptive
Summarise categorical variables
Outcome descriptive
Rechallenge descriptive
Time to onset descriptive
Read parquet and convert to data.table
Time to onset extraction
Get ATC codes (DrecNos or MPIs)
Get DrecNo from drug names or MedicinalProd_Id
Get low level term codes from SMQs
Get low level term codes from soc classification
Credibility interval limits for the information component
Nice printing of p-values
Screening of adverse drug reactions
Screening of drugs
Create MedDRA tables
Extract of subset of Vigibase
Create VigiBase ECL tables
Create WHO tables
Display routine pharmacovigilance summary
Deprecated functions in package vigicaen.
vigicaen: 'VigiBase' Pharmacovigilance Database Toolbox
Perform the analysis of the World Health Organization (WHO) Pharmacovigilance database 'VigiBase' (Extract Case Level version), <https://who-umc.org/> e.g., load data, perform data management, disproportionality analysis, and descriptive statistics. Intended for pharmacovigilance routine use or studies. This package is NOT supported nor reflect the opinion of the WHO, or the Uppsala Monitoring Centre. Disproportionality methods are described by Norén et al (2013) <doi:10.1177/0962280211403604>.
Useful links