Certara.RDarwin1.2.0 package

Interface for 'pyDarwin' Machine Learning Pharmacometric Model Development

add_Covariate

Add Covariate into PML models

add_CustomSpace

Add a Custom Space to a PMLModels Object

add_Dosepoint

Add Dosepoint in PML models

add_Spaces

Add Multiple Model Spaces to a PMLModels Object

add_StParm

Add Structural parameter into PML models Dosepoints

Covariate

Create a new Covariate object and validate it

create_CustomSpace

Create a Custom Space (PML Model) from Code

create_ModelEmax

Get the list of objects describing the PML models by set of Emax param...

create_ModelPD

Get the list of objects describing the PML models by set of PD paramet...

create_ModelPK

Get the list of objects describing the PML models by set of PK paramet...

create_pyDarwinOptions

Create pyDarwin Options

Dosepoint

Create a new Dosepoint object and validate it

Expression

Create an Expression object

get_ModelTermsToMap

Get Model Terms to Map

InitialEstimate

Create an object of class InitialEstimate

list_Covariates

List Covariates in the currrent PML set

list_Dosepoints

List Dosepoints in the current PML set

list_Observations

List Observations in the current PML set

list_Omegas

List Unique Omega Names

list_StParms

List Structural Parameters in the currrent PML set

list_Thetas

List Unique Theta Names

modify_Dosepoint

Modify Dosepoint in PML models

modify_Observation

Modify Observation class in PML models

modify_Omega

Modify Omega Parameters in PML Models

modify_StParm

Modify structural parameter in PML models set

modify_StParmCustom

Modify custom structural parameter in PML spaces

modify_Theta

Modify Theta Parameters in PML Models

Observation

Create an instance of Observation class.

ObservationCustom

Create an instance of custom Observation class.

Omega

Create an Omega instance with validation

output_NLMETemplate

Generate NLME Model Template from JSON Specification

output.CustomSpace

Output a Custom Space

pyDarwinOptionsGA

Create options for the Genetic Algorithm (GA) in pyDarwin.

pyDarwinOptionsGridAdapter

Grid Adapter Options for pyDarwin

pyDarwinOptionsMOGA

Create Options for the pyDarwin MOGA Block

pyDarwinOptionsPenalty

Create pyDarwin Penalty Options

pyDarwinOptionsPostprocess

Create pyDarwin Postprocess Options

pyDarwinOptionsPSO

Create options for the Particle Swarm Optimization (PSO) in pyDarwin.

reconnect_pyDarwinJob

Reconnect, Monitor, and Retrieve Results from a Remote pyDarwin Job

remove_Covariate

Remove Covariate from PML models

remove_Observation

Remove Observation from PML models

remove_StParm

Remove structural parameter from PML models

run_pyDarwin

Run pyDarwin Model Search

run_pyDarwinRemote

Run pyDarwin on a Remote Host via SSH

Sigmas

Create an instance of Sigmas class.

specify_EngineParams

Specify Engine Parameters for NLME Model Execution

specify_SimParams

Specify Engine Parameters for Model Simulation

stop_pyDarwin

Stop pyDarwin Model Search

stop_pyDarwinRemote

Stop a Remote pyDarwin Job

StParm

Create an instance of a Structural parameter.

Table

Class initializer for NLME tables

Theta

Create a new Theta instance with validation.

write_ModelTemplateTokens

Prints NLME metamodel template file and token json file using given op...

write_pyDarwinOptions

Write pyDarwin options to a JSON file.

Utilities that support the usage of 'pyDarwin' (<https://certara.github.io/pyDarwin/>) for ease of setup and execution of a machine learning based pharmacometric model search with Certara's Non-Linear Mixed Effects (NLME) modeling engine.