Correlation Guided Network Integration (CoNI)
Table VertexClass pairs of shared Edge Features
Correlation guided Network Integration
Number lipid features per class
Vertex-class pairs profile of one shared edge feature
Vertex-class pairs profile of shared features
Stacked Global Barplot (One treatment)
Bipartite Network
Bipartite Table
Delete intermediary files
Check if files exist
Stacked Global Barplot Side-by-side (two treatments)
Get vertexes for edge feature
Vertex Class profile per edge feature (one treatment)
Find local controlling features
Flatten
Create network
Low variance features
Get class rgb color
Assing Colors to Class
Number Vertex features per class for every shared edge feature
Output directory
Check previous files
Check input parameters
Split function
Compare sample names
Compare triplets
Network Statistics
Get colors
Correlation vs Partial correlation
Pairwise correlations
Significant correlations 2 Df
Split dataset
Table local controlling edge features and vertex pairs
Linker Features by magnitude of effect
Write table
Vertex-Class profile per edge feature Side-by-Side (two treatments)
Labels to colors
Merge Files.
Integrates two numerical omics data sets from the same samples using partial correlations. The output can be represented as a network, bipartite graph or a hypergraph structure. The method used in the package refers to Klaus et al (2021) <doi:10.1016/j.molmet.2021.101295>.