cubeHomingDrive function

Inheritance Cube: CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) with 2 Resistance Alleles and maternal deposition

This is a sex-specific version of the original cube cubeHoming1RA. It assumes that the construct is on an autosome and there can be different male/female homing rates. It also has maternal deposition, i.e., when the male provides a W allele to a female with a H allele, some portion are cut during oogenesis. If the maternal deposition parameters are zero (d* parameters), this is a normal CRISPR drive.

cubeHomingDrive(
  cM = 1,
  cF = 1,
  dF = 0,
  chM = 0,
  crM = 0,
  chF = 0,
  crF = 0,
  dhF = 0,
  drF = 0,
  eta = NULL,
  phi = NULL,
  omega = NULL,
  xiF = NULL,
  xiM = NULL,
  s = NULL
)

Arguments

• cM: Male homing rate
• cF: Female homing rate
• dF: Female deposition homing rate
• chM: Male correct homing rate
• crM: Male resistance generating rate
• chF: Female correct homing rate
• crF: Female resistance generating rate
• dhF: Female correct deposition rate
• drF: Female resistance deposition rate
• eta: Genotype-specific mating fitness
• phi: Genotype-specific sex ratio at emergence
• omega: Genotype-specific multiplicative modifier of adult mortality
• xiF: Genotype-specific female pupatory success
• xiM: Genotype-specific male pupatory success
• s: Genotype-specific fractional reduction(increase) in fertility

Returns

Named list containing the inheritance cube, transition matrix, genotypes, wild-type allele, and all genotype-specific parameters.