Mosquito Gene Drive Explorer
Aggregate Female Output by Genotype
Aggregate Output Over Landscape
Make List of Batch Migration Parameters
Make List of Modified Mosquito Releases
Calculate Aquatic Stage Survival Probability
Calculate Average Generation Time
Calculate Geodesic Distance - Cosine Method
Calculate Density-dependent Larval Mortality
Calculate Exponential Stochastic Matrix
Calculate Gamma Stochastic Matrix
Calculate Geodesic Distance - Haversine Method
Calculate Zero-inflated Exponential Stochastic Matrix
Calculate Distribution of Larval Population
Calculate Equilibrium Larval Population
Calculate Larval Stage Mortality Rate
Calculate Lognormal Stochastic Matrix
Solve for Omega (additional genotype-specific mortality)
Calculate Generational Population Growth Rate
Summary Statistics for Stochastic MGDrivE
Calculate Geodesic Distance - Vincenty Ellipsoid Method
Calculate Geodesic Distance - Vincenty Sphere Method
Calculates the zero-inflation part of a hurdle exponential kernel.
Export a Cube to .csv
Inheritance Cube: ClvR (Cleave and Rescue)
Inheritance Cube: 2-Locus ClvR (Cleave and Rescue)
Inheritance Cube: ECHACR
Inheritance Cube: ECHACRX
Inheritance Cube: Homing Drive with 1 Resistance Allele
Inheritance Cube: CRISPR (Clustered Regularly Interspaced Short Palind...
Inheritance Cube: Killer-Rescue System
Inheritance Cube: MEDEA (Maternal Effect Dominant Embryonic Arrest)
Inheritance Cube: Mendelian
Generate and Modify Default Genotype-specific Parameters
Inheritance Cube: 1 Locus Maternal-Toxin/Zygotic-Antidote System
Inheritance Cube: Reciprocal Translocation
Inheritance Cube: RIDL (Release of Insects with Dominant Lethality)
Inheritance Cube: Split CRISPR drive with 2 Resistance Alleles and mal...
Inheritance Cube: tGD
Inheritance Cube: tGDX
Inheritance Cube: 2 Locus Maternal-Toxin/Zygotic-Antidote System
Inheritance Cube: Wolbachia
Erase all files in a directory
Make List of Modified Mosquito Releases
Get alpha
Get beta
Get conADF
Get conADM
Get Element(s) of Drive Cube by Index
Get eta
Get female Population
Get genotypesID
Get genotypesN
Get male Population
Get muAd
Get muAq
Get nPatch
Get omega
Get Patch Release Schedule
Get phi
Get s
Get Female Viability Mask (tau)
Get timeAq
Get tNow
Get xiF
Get xiM
Utility to Imitate ggplot2 Colors
MGDrivE: Inheritance Cube
MGDrivE: Model's Mathematical Description
MGDrivE: Mosquito Gene Drive Explorer
Run Simulation
Network Class Definition
Normalise a Numeric Vector
Deterministic Adult Survival
Stochastic Adult Survival
Deterministic Egg Death and Pupation
Stochastic Egg Death and Pupation
Release Eggs in a Patch
Initialize Output from Focal Patch
Deterministic Larva Death and Pupation
Stochastic Larva Death and Pupation
Deterministic Mating
Stochastic Mating
Deterministic Inter-Patch Migration
Stochastic Inter-Patch Migration
Inbound Migration
Run a Single Day on a Network
Deterministic Oviposition
Stochastic Oviposition
Daily Population Dynamics for a Patch
Deterministic Pupa Death and Pupation
Stochastic Pupa Death and Pupation
Deterministic Pupation
Stochastic Pupation
Release Male/Female/Mated-Female Mosquitoes in a Patch
Write Output from Focal Patch
Run Simulation
parameterizeMGDrivE
Patch Class Definition
Plot
Plot
Quantiles Function
Dirichlet Distribution
Reset Network
Reset Patch to Initial Conditions
Retrieve Output
Set Initial Population
Set Network Pointer
Set Initial Population Deterministic
Set Initial Population Stochastic
Setup MGDrivE
Split Output by Patch
Provides a model designed to be a reliable testbed where various gene drive interventions for mosquito-borne diseases control. It is being developed to accommodate the use of various mosquito-specific gene drive systems within a population dynamics framework that allows migration of individuals between patches in landscape. Previous work developing the population dynamics can be found in Deredec et al. (2001) <doi:10.1073/pnas.1110717108> and Hancock & Godfray (2007) <doi:10.1186/1475-2875-6-98>, and extensions to accommodate CRISPR homing dynamics in Marshall et al. (2017) <doi:10.1038/s41598-017-02744-7>.
Useful links