cubeKillerRescue function

Inheritance Cube: Killer-Rescue System

This function creates an inheritance cube to model a Killer-Rescue system. Killer-Rescue is a 2-locus system: one locus has a toxin and the other locus contains the antidote. The loci are assumed independent and are non-homing.

This drive has 3 alleles at locus 1 and 2 alleles and locus 2:

• Locus 1

  • T: Wild-type allele
  • K: "Killer" toxin allele
  • R: Broken toxin allele

• Locus 2

  • W: Wild-type allele
  • A: Antidote allele

cubeKillerRescue(
  eR = 0,
  Keff = 1,
  Aeff = 1,
  eta = NULL,
  phi = NULL,
  omega = NULL,
  xiF = NULL,
  xiM = NULL,
  s = NULL
)

Arguments

• eR: Conversion of K allele to R allele, a basal mutation rate
• Keff: Toxin efficacy
• Aeff: Antidote efficacy
• eta: Genotype-specific mating fitness
• phi: Genotype-specific sex ratio at emergence
• omega: Genotype-specific multiplicative modifier of adult mortality
• xiF: Genotype-specific female pupatory success
• xiM: Genotype-specific male pupatory success
• s: Genotype-specific fractional reduction(increase) in fertility

Returns

Named list containing the inheritance cube, transition matrix, genotypes, wild-type allele, and all genotype-specific parameters.