MRHetPen Class
An object containing the estimate produced using the heterogeneity-penalized model-averaging mode-based estimation method as well as various statistics. class
Exposure
: The names of the exposure variables.Outcome
: The name of the outcome variable.Prior
: The value of the prior probability of a genetic variant being a valid instrument (default is 0.5).Estimate
: The causal estimate from the heterogeneity-penalized method.CIRange
: The confidence interval for Estimate
based on a grid search.CILower
: The lower limit of the confidence interval. If the confidence interval contains multiple ranges, then lower limits of all ranges will be reported.CIUpper
: The upper limit of the confidence interval. If the confidence interval contains multiple ranges, then upper limits of all ranges will be reported.CIMin
: The smallest value used in the search to find the confidence interval.CIMax
: The largest value used in the search to find the confidence interval.CIStep
: The step size used in the search to find the confidence interval.Alpha
: The significance level used in constructing the confidence interval (default is 0.05).SNPs
: The number of SNPs that were used in the calculation.Useful links