MRHetPen-class function

MRHetPen Class

MRHetPen Class

An object containing the estimate produced using the heterogeneity-penalized model-averaging mode-based estimation method as well as various statistics. class

Slots

  • Exposure: The names of the exposure variables.
  • Outcome: The name of the outcome variable.
  • Prior: The value of the prior probability of a genetic variant being a valid instrument (default is 0.5).
  • Estimate: The causal estimate from the heterogeneity-penalized method.
  • CIRange: The confidence interval for Estimate based on a grid search.
  • CILower: The lower limit of the confidence interval. If the confidence interval contains multiple ranges, then lower limits of all ranges will be reported.
  • CIUpper: The upper limit of the confidence interval. If the confidence interval contains multiple ranges, then upper limits of all ranges will be reported.
  • CIMin: The smallest value used in the search to find the confidence interval.
  • CIMax: The largest value used in the search to find the confidence interval.
  • CIStep: The step size used in the search to find the confidence interval.
  • Alpha: The significance level used in constructing the confidence interval (default is 0.05).
  • SNPs: The number of SNPs that were used in the calculation.
  • Maintainer: Stephen Burgess
  • License: GPL-2 | GPL-3
  • Last published: 2024-04-12

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