R01.3-1 package

Estimation of R0 and Real-Time Reproduction Number from Epidemics

censored.deviation

Deviation between theorietical incidence and observed data.

check.incid

Check incidence vector in the input

est.GT

Estimate generation time distribution

est.R0.AR

Estimate R0 from attack rate of an epidemic

est.R0.EG

Estimate R0 from exponential growth rate of an epidemic

est.R0.ML

Estimate R0 by Maximum Likelihood

est.R0.SB

Estimate the time dependent R using a Bayesian method

est.R0.TD

Estimate the Time-Dependent reproduction number

estimate.R

Estimate reproduction number (R0 or Rt) for one incidence dataset usin...

fit.epid.optim

Joint estimation of R and generation time distribution for the ML meth...

fit.epid

Poisson log-likelihood for an observed epidemic

generation.time

Generation Time distribution

get.scale

Scaling of x-axis

impute.incid

Impute censored cases to rebuild longer epidemic vector

inspect.data

Audit input data for common issues

integrity.checks

Integrity checks for input parameters

plot.R0.GT

Plot a generation time distribution

plot.R0.R

Plot the R0/Rt value along with confidence interval

plot.R0.S

Plot of sensitivity analyses.

plot.R0.sR

Plot the R0/Rt value along with confidence interval

plotfit.R0.R

Plot a model fit for R0.R objects

plotfit.R0.sR

Plot a model fit for R0.sR objects

plotfit

S3 method for objects of class R0.R or R0.sR

plotfitRAR

Internal plotfit method for AR estimates

plotfitRSB

Internal plotfit method for AR estimates

plotfitRxx

Internal plotfit method for EG, ML and TD estimates

plotRAR

Plot R0 for Attack Rate method

plotREG

Plot R0 for Exponential Growth method

plotRML

Plot R0 for Maximum Likelihood method

plotRSB

Plot R0 for Sequential Bayesian method

plotRTD

Plot R0 for Time-Dependent method

print.R0.GT

Print method for objects of class R0.GT

print.R0.R

Print method for objects of class R0.R

print.R0.sR

Print method for objects of class R0.sR

R.from.r

Estimate reproduction number from exponential growth rate

sa.GT

Sensitivity of R0 to varying generation time distributions

sa.time

Sensitivity of R0 to time estimation windows

sensitivity.analysis

Sensitivity analysis of basic reproduction ratio to begin/end dates

sim.epid.indiv

Influenza-like illness simulation (individual-based model)

sim.epid

Epidemic outbreak simulation

smooth.Rt

Smooth real-time reproduction number over larger time periods

Estimation of reproduction numbers for disease outbreak, based on incidence data. The R0 package implements several documented methods. It is therefore possible to compare estimations according to the methods used. Depending on the methods requested by user, basic reproduction number (commonly denoted as R0) or real-time reproduction number (referred to as R(t)) is computed, along with a 95% Confidence Interval. Plotting outputs will give different graphs depending on the methods requested : basic reproductive number estimations will only show the epidemic curve (collected data) and an adjusted model, whereas real-time methods will also show the R(t) variations throughout the outbreak time period. Sensitivity analysis tools are also provided, and allow for investigating effects of varying Generation Time distribution or time window on estimates.