Single-Cell RNA-Seq Gene Expression Recovery
Samples from SAVER
SAVER: Single-cell Analysis Via Expression Recovery
Calculate maximum correlation
Calculates SAVER posterior
Calculate estimate
Calculates marginal likelihood
Combines SAVER
Calculates gene-to-gene and cell-to-cell SAVER correlation
Calculates SAVER prediction.
Output prior predictions
Optimizes variance
Runs SAVER
Fits SAVER
An implementation of a regularized regression prediction and empirical Bayes method to recover the true gene expression profile in noisy and sparse single-cell RNA-seq data. See Huang M, et al (2018) <doi:10.1038/s41592-018-0033-z> for more details.