Plot the operating characteristics from a standard 3+3 trial
Plot the operating characteristics from a standard 3+3 trial
Plots of the operating characteristics obtained from a standard 3+3 trial, using threep3
## S3 method for class 'threep3'plot(x, file =NULL,...)
Arguments
x: An object of class "threep3", as returned by threep3.
file: File name where the operating characteristic plot is stored, in a pdf format.
...: Further arguments passed to or from other methods
Details
This function plots the sample size distribution, the experimentation distribution, the recommended dose distribution and the percentage of subjects who experience the toxicity outcome (dose-limiting toxicity) for the standard 3+3 trial.
References
Sweeting M., Mander A., Sabin T. bcrm: Bayesian Continual Reassessment Method Designs for Phase I Dose-Finding Trials. Journal of Statistical Software (2013) 54: 1--26. http://www.jstatsoft.org/article/view/v054i13