coxmeMlist function

Coxme variance function

This variance function accepts a list of matrices, which define a correlation structure for a coxme fit. 1.1

coxmeMlist(varlist, rescale = FALSE, pdcheck = TRUE, positive = TRUE)

Arguments

• varlist: a list containing one or more matrix or bdsmatrix objects.
• rescale: if TRUE, each input matrix is rescaled to have a diagonal of 1. (Kinship matrices for instance are often generated with a diagonal of .5 and would be multiplied by 2).
• pdcheck: check each matrix to ensure that it is positive definite
• positive: constrain coefficients to be positive. This may also be a vector of the same length as varlist

Details

If two matrices $A$ and $B$ were given, this fits the variance structure $V = s1 A + s2 B$, where the variances $s1$ and $s2$ are parameters that will be optimized by coxme, treating $A$ and $B$ as fixed.

Returns

a coxme variance family object, used by coxme in the fitting process.

Author(s)

Terry Therneau

See Also

coxme