pdlt_d1extended function

Generating a probability of DLT function based on the EWOC extended model

pdlt_d1extended(rho, min_dose, max_dose)

Arguments

• rho: a numerical vector indicating the true value of the parameters rho_0 and rho_1.
• min_dose: a numerical value defining the lower bound of the support of the MTD.
• max_dose: a numerical value defining the upper bound of the support of the MTD.

Returns

A function with dose as an input and a probability based on the logistic regression and parameters as an output.

Examples

pdlt <- pdlt_d1extended(rho = c(0.05, 0.5),
                       min_dose = 10, max_dose = 50)
pdlt(20)