Plaque psoriasis data
Two data frames, plaque_psoriasis_ipd and plaque_psoriasis_agd, containing (simulated) individual patient data from four studies and aggregate data from five studies \insertCite Phillippo_thesismultinma. Outcomes are binary success/failure to achieve 75%, 90%, or 100% reduction in symptoms on the Psoriasis Area and Severity Index (PASI) scale.
data
Format
The individual patient data are contained in a data frame plaque_psoriasis_ipd with 4118 rows, one per individual, and 16 variables:
- studyc: study name
- trtc_long: treatment name (long format)
- trtc: treatment name
- trtn: numeric treatment code
- pasi75: binary PASI 75 outcome
- pasi90: binary PASI 90 outcome
- pasi100: binary PASI 100 outcome
- age: age (years)
- bmi: body mass index (BMI)
- pasi_w0: PASI score at week 0
- male: male sex (TRUE or FALSE)
- bsa: body surface area (percent)
- weight: weight (kilograms)
- durnpso: duration of psoriasis (years)
- prevsys: previous systemic treatment (TRUE or FALSE)
- psa: psoriatic arthritis (TRUE or FALSE)
The aggregate data are contained in a data frame plaque_psoriasis_agd with 15 rows, one per study arm, and 26 variables:
- studyc: study name
- trtc_long: treatment name (long format)
- trtc: treatment name
- trtn: numeric treatment code
- pasi75_r, pasi75_n: PASI 75 outcome count and denominator
- pasi90_r, pasi90_n: PASI 75 outcome count and denominator
- pasi100_r, pasi100_n: PASI 75 outcome count and denominator
- sample_size_w0: sample size at week zero
- age_mean, age_sd: mean and standard deviation of age (years)
- bmi_mean, bmi_sd: mean and standard deviation of BMI
- pasi_w0_mean, pasi_w0_sd: mean and standard deviation of PASI score at week 0
- male: percentage of males
- bsa_mean, bsa_sd: mean and standard deviation of body surface area (percent)
- weight_mean, weight_sd: mean and standard deviation of weight (kilograms)
- durnpso_mean, durnpso_sd: mean and standard deviation of duration of psoriasis (years)
- prevsys: percentage of individuals with previous systemic treatment
- psa: percentage of individuals with psoriatic arthritis
An object of class data.frame with 15 rows and 26 columns.
plaque_psoriasis_ipd
plaque_psoriasis_agd
References
\insertAllCited