outstandR1.0.0 package

Model-Based Standardisation for Indirect Treatment Comparison with Limited Subject-Level Data

calc_ALD_stats

Aggregate-level data mean and variance statistics

calc_gcomp_bayes

Bayesian G-computation using Stan

calc_gcomp_ml

G-computation Maximum Likelihood Bootstrap

calc_IPD_stats

Calculate individual-level patient data statistics

calc_maic

Calculate MAIC

calc_mim

Multiple imputation marginalization (MIM)

calc_stc

Calculate simulated treatment comparison statistics

calculate_ate

Calculate Average Treatment Effect

calculate_trial_mean_binary

Calculate Trial Mean Binary Data

calculate_trial_mean_continuous

Calculate Trial Mean Continuous Data

calculate_trial_mean_count

Calculate Trial Mean Count Data

calculate_trial_mean

Calculate Trial Mean Wrapper

calculate_trial_variance_binary

Calculate trial variance binary

calculate_trial_variance_continuous

Calculate trial variance continuous

calculate_trial_variance_count

Calculate trial variance count

calculate_trial_variance

Calculate trial variance

check_formula

Check formula

continuity_correction

Continuity Correction

cor2cov

Compute covariance matrix

estimate_var_sandwich

Estimate Variance Sandwich Estimator

gcomp_ml_means

G-computation maximum likelihood mean outcomes by arm

gcomp_ml.boot

Bootstrap for G-computation via Maximum Likelihood

get_allowed_var_methods

Retrieve list of allowed variance methods

get_comparator

Get study comparator treatment names

get_covariate_names

Get covariate names

get_eff_mod_names

Get effect modifiers

get_ref_trt

Get reference treatment

get_robust_vcov

Compute Robust Covariance Matrix (HC0-style)

get_treatment_effect

Get treatment effect scale corresponding to a link function

get_treatment_name

Get treatment name

get_var_method

Determine and validate variance method for a strategy

guess_treatment_name

Guess treatment name

IPD_stat_factory

Factory function for creating calc_IPD_stats methods

maic_weights

Estimate MAIC weights

maic.boot

MAIC bootstrap sample

marginal_treatment_effect

Marginal treatment effect from reported event counts

marginal_variance

Marginal effect variance using the delta method

num_grad

Numerical Gradient

outstandR-class

outstandR class

outstandR-package

outstandR: Model-Based Standardisation for Indirect Treatment Comparis...

outstandR

Calculate the difference between treatments using all evidence

plot.outstandR

Default Plot Method for outstandR Objects

prep_ald

Prepare Aggregate Level Data

prep_ipd

Prepare Individual Patient Data

prepare_covariate_distns

Prepare Covariate Distributions

print.outstandR

Print a Summary of a outstandR Object

Q

Objective function to minimize for standard method of moments MAIC

reshape_ald_to_long

Convert aggregate data from wide to long format

reshape_ald_to_wide

Convert aggregate data from long to wide format

result_stats

Calculate and arrange result statistics

simulate_ALD_pseudo_pop

Simulate Aggregate-Level Data Pseudo-Population

strategy-class

Strategy class and subclasses

strategy

New strategy objects

summary.outstandR

Summary method for outstandR

validate_outstandr

Input data validator

var_by_pooling

Variance estimate by pooling

wald_type_interval

Wald-type interval estimates

For the problem of indirect treatment comparison with limited subject-level data, this package provides tools for model-based standardisation with several different computation approaches. See Remiro‐Azócar A, Heath A, Baio G (2022) "Parametric G‐computation for compatible indirect treatment comparisons with limited individual patient data", Res. Synth. Methods, 1–31. ISSN 1759-2879, <doi:10.1002/jrsm.1565>.

  • Maintainer: Nathan Green
  • License: GPL (>= 3)
  • Last published: 2026-01-21