Fast Sequential Pleiotropy Test
Internal function to identify sub-sets of data and return a list with ...
Single Trait Manhattan plot
Multi-trait Genome wide association model.
Plot ideogram from pleio_test results
Pleiotropic manhattan plot
Create simulations
Sequential Wald test for pleiotropy
Fit a multi-trait model to test for genetic pleiotropy
Calculate XRsX and XRsY
It performs a fast multi-trait genome-wide association analysis based on seemingly unrelated regressions. It tests for pleiotropic effects based on a series of Intersection-Union Wald tests. The package can handle large and unbalanced data and plot results.