Represents the randomization procedure Accelerated Biased Coin Design.
abcdPar(N, a, groups = LETTERS[1:2])
Arguments
N: integer for the total sample size of the trial.
a: nonnegative parameter which controls the degree of randomness: For decreasing a the allocations become deterministic, while for increasing a the randomization procedure tends to complete randomization.
groups: character vector of labels for the different treatments.
Returns
S4 object of the class abcdPar.
Details
This is a class of 'biased coins' where the probability of selecting the under-represented treatment is dependent from the absolute difference between the two treatment allocations up to the current step.
References
A. B. Antognini and A. Giovagnoli (2004) A new 'biased coin design' for the sequential allocation of two treatments. Journal of the Royal Statistical Society. Series C (Applied Statistics)