Randomization for Clinical Trials
Function returning the adjusting parameter a slot of an S4 object
Representing Accelerated Biased Coin Design
Sampling algorithm for abcd
Creates stratified sequences Compares stratified sequences to their re...
Assessing randomization sequences
Representing Bayesian Biased Coin Design
Sampling algorithm for bbcd
Function returning the block slot of an S4 object
Representing Big Stick Design
Sampling algorithm for BSD
Method defining the $ operator for the assessment class
Method defining the $ operator for the assessment class
Method defining the $ operator for the derFunc class
Method defining the $ operator for the desFunc class
Method defining the $ operator for the assessment class
Method defining the $ operator for the endpoint class
Method defining the $ operator for the evaluation class
Method defining the $ operator for the issue class
Method defining the $ operator for the probUnDesirable class
Method defining the $ operator for the randPar class
Method defining the $ operator for the randSeq class
Representing Chen's Design
Representing Chen's Design
Representing chronological bias
Function returning the coin slot of an S4 object
Combined bias criterion
Comparison of randomization procedures
Representing the expected number of correct guesses
Representing any randomization procedure
Query to create a randomization sequence of a particular randomization...
Representing Complete Randomization
Representing Derringer-Suich desirability functions
Desirability functions within the scope of clinical trials
Distribution function of the non central F-distribution
Rejection probability for one sequence in the presence of selection bi...
Rejection probability in case of selection bias in multi-arm trials
Approximation of the distribution function of the doubly noncentral t-...
Calculation of the biased type-one-error probability (resp. power) of ...
Representing Efron's Biased Coin Design
Evaluation of several randomization procedures with respect to certain...
Representation of exponentially distributed endpoints
Representing Generalized Biased Coin Design
Sampling algorithm for gbcd
Complete set of randomization sequences
Generate random sequences
Calculation of the NCPs of each randomization sequence for the doubly ...
Calculation of the NCPs of each randomization sequence for the doubly ...
Calculating p values
Biasing Policy for a Group of Favored Treatments
Biasing Policy for Avoiding the Placebo Treatment
Matrix of the guesses of the investigator
Type of Desirability function
Design of a randomization procedure
Applying desirability functions on issues of individual randomization ...
Get distribution parameters of a randomization list
Get expectations of a randomization list
Theoretical probability for randomization sequences
Accessor function for the randomization list
Calculates the Type I error for different randomization sequences from...
Calculates the Type I error for a randomization sequence in a group se...
Representing Hadamard Randomization
Check function for occurrence of all treatment groups in the sequence
Calculate hat matrix
Representing the allocation imbalance
Assessment criteria for clinical trials
Function returning the number of trial arms slot of an S4 object
Method returning the rate parameter of an expEndp S4 object
Calculate first non centrality parameter of the doubly non central F-d...
Calculate second non centrality parameter of the doubly non central F-...
logRankDecSim
Approximation of the biased type I error probability (resp. power) of ...
Calculate Expectation vector
Design Matrix
Function returning the method of an S4 object
Representing Maximal Procedure
Function returning the MTI slot of an S4 object
Access the expectation value slot of a normEndp S4 object
Function returning the sample size slot of an S4 object
Representation of normally distributed endpoints
Overview over the parameters used in the randomizeR
package
Representing Permuted Block Randomization
Generic plotting of comparison objects
desScore plotting
Evaluation plotting
Sequence plotting
Computing the probability of having desirability scores of zero
Function returning the block slot of an S4 object
Randomization for Clinical Trials
Settings for randomization procedures
An S4 Class for the representation of randomization sequences
Representing Random Allocation Rule
Function returning the allocation ratio slot of an S4 object
Function returning the adjusting parameter rho slot of an S4 object
Representing Randomized Permuted Block Randomization
Representing Randomized Truncated Binomial Design
Saving an assess object
Saving a randomization lists
Method returning the scale parameter of an survEndp S4 object
Function returning the allocation seed slot of an object
Representing selection bias
Representing the power
Method returning the shape parameter of an survEndp S4 object
Function returning the standard deviation slot of a normEndp S4 object
Summary of assessments of a randomization procedure
Representation of survival endpoints
Representing Truncated Binomal Design
Function returning the target value slot of an S4 object
Get type of an object
Representing Wei's Urn Design
This tool enables the user to choose a randomization procedure based on sound scientific criteria. It comprises the generation of randomization sequences as well the assessment of randomization procedures based on carefully selected criteria. Furthermore, 'randomizeR' provides a function for the comparison of randomization procedures.