bc: vector which contains the lengths k_1,...,k_l of each block. This means that the vector bc will have one entry for each block.
groups: character vector of labels for the different treatments.
Returns
S4 object of the class tbdPar.
Details
A fair coin is tossed until half of the patients have been assigned to one of the treatment arms. Afterwards, the randomization list is filled with the other treatment.
References
W. F. Rosenberger and J. M. Lachin (2002) Randomization in Clinical Trials. Wiley.