createParam function

Representing any randomization procedure

Represents any randomization procedure for a two-armed clinical trial.

createParam(method, N, mti, bc, rb, p, ini, add, filledBlock)

Arguments

• method: method that is used to generate the (random) allocation sequence. It can take values PBR, RAR, HAD, PWR, EBC, BSD, CR, TBD, UD, and MP.
• N: integer for the total sample size of the trial.
• mti: maximum tolerated imbalance in patient numbers during the trial.
• bc: vector which contains the lengths k_1,...,k_l of each block. This means that the vector bc will have one entry for each block.
• rb: block lengths of the blocks that can be selected equiprobable at random.
• p: success probability of the biased coin (e.g. in Efron's Biased Coin Design).
• ini: integer representing the initial urn composition.
• add: integer representing the number of balls that are added to the urn in each step.
• filledBlock: logical whether the last block should be filled or not.

Returns

S4object of the corresponding randomization procedure class.

Details

Depending on the input of the user, createParam creates an object representing a randomization procedures for a two-armed clinical trial (see also randPar).

See Also

Other randomization procedures: abcdPar, bbcdPar, bsdPar, chenPar, crPar, ebcPar, gbcdPar, hadaPar, mpPar, pbrPar, rarPar, rpbrPar, rtbdPar, tbdPar, udPar