Represents the randomization procedure Random Allocation Rule.
rarPar(N, K =2, ratio = rep(1, K), groups = LETTERS[1:K])
Arguments
N: integer for the total sample size of the trial.
K: number of treatment groups (e.g. K=2 if we compare one experimental against one control treatment).
ratio: vector of length K. The total sample number N and all used block lengths (bc) have to be divisible by sum(ratio).
groups: character vector of labels for the different treatments.
Returns
S4 object of the class rarPar.
Details
Fix a total sample size N the number of treatment groups K, and the vector of the ratio. Afterwards, all patients are assigned according to the ratio to the corresponding treatment groups. All randomization sequences are equiprobable.
References
W. F. Rosenberger and J. M. Lachin (2002) Randomization in Clinical Trials. Wiley.