hadaPar function

Representing Hadamard Randomization

Represents the randomization procedure Hadamard Randomization.

hadaPar(N, groups = LETTERS[1:2])

Arguments

• N: integer for the total sample size of the trial.
• groups: character vector of labels for the different treatments.

Returns

S4 object of the class hadaPar.

Details

Hadamard randomization has been proposed by R.A. Bailey. The key idea is to use the columns of a special Hadamard Matrix as a randomization scheme. The implemented algorithm uses the Hadamard Matrix with N=12 columns proposed in the paper, see references.

Note

getProb and getAllSeq are currently only supported for hadaPar

with total sample size N=12.

References

R.A. Bailey and P.R. Nelson (2003) Hadamard Randomization: A valid restriction of random permuted blocks. Biometrical Journal, 45 , 554-60.

See Also

Other randomization procedures: abcdPar, bbcdPar, bsdPar, chenPar, crPar, createParam(), ebcPar, gbcdPar, mpPar, pbrPar, rarPar, rpbrPar, rtbdPar, tbdPar, udPar