scoper-package

scoper: Spectral Clustering-Based Method for Identifying B Cell Clones

Provides a computational framework for identification of B cell clones from Adaptive Immune Receptor Repertoire sequencing (AIRR-Seq) data. Three main functions are included (identicalClones, hierarchicalClones, and spectralClones) that perform clustering among sequences of BCRs/IGs (B cell receptors/immunoglobulins) which share the same V gene, J gene and junction length. Nouri N and Kleinstein SH (2018) tools:::Rd_expr_doi(" 10.1093/bioinformatics/bty235") . Nouri N and Kleinstein SH (2019) tools:::Rd_expr_doi(" 10.1101/788620") . Gupta NT, et al. (2017) tools:::Rd_expr_doi(" 10.4049/jimmunol.1601850") . package

See Also

Useful links:

• https://scoper.readthedocs.io
• Report bugs at https://bitbucket.org/kleinstein/scoper/issues

Author(s)

Maintainer : Susanna Marquez susanna.marquez@yale.edu [contributor]

Authors:

• Nima Nouri nima.nouri@yale.edu
• Jason Vander Heiden jason.vanderheiden@gmail.com
• Steven Kleinstein steven.kleinstein@yale.edu [copyright holder]

Other contributors:

• Edel Aron edel.aron@yale.edu [contributor]
• Gisela Gabernet gisela.gabernet@yale.edu [contributor]