Clinical Trial Design, Monitoring, and Analysis - CRAN Task View

accrualPlot

Accrual Plots and Predictions for Clinical Trials

Version 1.0.7

adaptTest

Adaptive Two-Stage Tests

Version 1.2

asd

Simulations for Adaptive Seamless Designs

Version 2.2

bcrm

Bayesian Continual Reassessment Method for Phase I Dose-Escalation Tri...

Version 0.5.4

blockrand

Randomization for Block Random Clinical Trials

Version 1.5

CRM

Continual Reassessment Method (CRM) for Phase I Clinical Trials

Version 1.2.4

clinfun

Clinical Trial Design and Data Analysis Functions

Version 1.1.5

clinsig

Clinical Significance Functions

Version 1.2

coin

Conditional Inference Procedures in a Permutation Test Framework

Version 1.4-3

conf.design

Construction of factorial designs

Version 2.0.0

cosa

Bound Constrained Optimal Sample Size Allocation

Version 2.1.0

dfcrm

Dose-Finding by the Continual Reassessment Method

Version 0.2-2.1

ewoc

Escalation with Overdose Control

Version 0.3.0

dfped

Extrapolation and Bridging of Adult Information in Early Phase Dose-Fi...

Version 1.1

DoseFinding

Planning and Analyzing Dose Finding Experiments

Version 1.2-1

multcomp

Simultaneous Inference in General Parametric Models

Version 1.4-26

epibasix

Elementary Epidemiological Functions for Epidemiology and Biostatistic...

Version 1.5

experiment

R Package for Designing and Analyzing Randomized Experiments

Version 1.2.1

FrF2

Fractional Factorial Designs with 2-Level Factors

Version 2.3-3

ldbounds

Lan-DeMets Method for Group Sequential Boundaries

Version 2.0.2

longpower

Sample Size Calculations for Longitudinal Data

Version 1.0.27

MCPMod

Design and Analysis of Dose-Finding Studies

Version 1.0-10.1

Mediana

Clinical Trial Simulations

Version 1.0.8

meta

General Package for Meta-Analysis

Version 7.0-0

metaLik

Likelihood Inference in Meta-Analysis and Meta-Regression Models

Version 0.43.0

metasens

Statistical Methods for Sensitivity Analysis in Meta-Analysis

Version 1.5-2

MinEDfind

A Bayesian Design for Minimum Effective Dosing-Finding Trial

Version 0.1.3

nppbib

Nonparametric Partially-Balanced Incomplete Block Design Analysis

Version 1.2-0

presize

Precision Based Sample Size Calculation

Version 0.3.7

rbmi

Reference Based Multiple Imputation

Version 1.2.6

randomizeR

Randomization for Clinical Trials

Version 3.0.2

UnifiedDoseFinding

Dose-Finding Methods for Non-Binary Outcomes

Version 0.1.10

speff2trial

Semiparametric Efficient Estimation for a Two-Sample Treatment Effect

Version 1.0.5

replicateBE

Average Bioequivalence with Expanding Limits (ABEL)

Version 1.1.3

simglm

Simulate Models Based on the Generalized Linear Model

Version 0.8.9

adaptr

Adaptive Trial Simulator

Version 1.4.0

TrialSize

R Functions for Chapter 3,4,6,7,9,10,11,12,14,15 of Sample Size Calcul...

Version 1.4

pwr

Basic Functions for Power Analysis

Version 1.3-0

rmeta

Meta-Analysis

Version 3.0

samplesize

Sample Size Calculation for Various t-Tests and Wilcoxon-Test

Version 0.2-4

TEQR

Target Equivalence Range Design

Version 6.0-0

ThreeGroups

ML Estimator for Baseline-Placebo-Treatment (Three-Group) Experiments

Version 0.21

ssanv

Sample Size Adjusted for Nonadherence or Variability of Input Paramete...

Version 1.1

PowerUpR

Power Analysis Tools for Multilevel Randomized Experiments

Version 1.1.0

clinicalsignificance

A Toolbox for Clinical Significance Analyses in Intervention Studies

Version 2.0.0

PowerTOST

Power and Sample Size for (Bio)Equivalence Studies

Version 1.5-6

metafor

Meta-Analysis Package for R

Version 4.6-0

survival

Survival Analysis

Version 3.7-0

rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

Version 4.1.0

Hmisc

Harrell Miscellaneous

Version 5.1-3

DTAT

Dose Titration Algorithm Tuning

Version 0.3-7

mmrm

Mixed Models for Repeated Measures

Version 0.3.14

ctrdata

Retrieve and Analyze Clinical Trials in Public Registers

Version 1.19.4

crmPack

Object-Oriented Implementation of CRM Designs

Version 1.0.6

HH

Statistical Analysis and Data Display: Heiberger and Holland

Version 3.1-52